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Pharmacology and Toxicology
N,N-dimethylacetamide blocks inflammation-induced preterm birth and remediates maternal systemic immune responses
10 March 2025 by
S. Reznik
and
others
Pharmacology and Toxicology
Baicalein ameliorates experimental ulcerative colitis recurrency by downregulating neonatal Fc receptor via the NF-κB signaling pathway
8 March 2025 by
Huping Hu
and
others
Pharmacology and Toxicology
Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
5 March 2025 by
D. Sarti
and
others
Pharmacology and Toxicology
Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi
1 March 2025 by
T. Chhibber
and
others
Pharmacology and Toxicology
GPCRVS - AI-driven decision support system for GPCR virtual screening
28 February 2025 by
D. Latek
and
others
at
University of Warsaw
Pharmacology and Toxicology
Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology
27 February 2025 by
P. Michaelis
and
others
Pharmacology and Toxicology
Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress
25 February 2025 by
T. T. M. Nhung
and
others
Pharmacology and Toxicology
Immunogenicity of Rabies Virus G-Protein mRNA Formulated with Muscle Targeting Lipid Nanoparticles in Mice
24 February 2025 by
Qing Li
and
others
Pharmacology and Toxicology
Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage and regeneration response after cisplatin
21 February 2025 by
L. Wijaya
and
others
at
Leiden University
Pharmacology and Toxicology
Pharmacokinetics of Extended-release Buprenorphine (Ethiqa) in Female Yorkshire Swine (Sus scrofa domestica)
21 February 2025 by
L. Stevey-Rindenow
and
others
at
University of Southern California
Pharmacology and Toxicology
Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
20 February 2025 by
A. Joushomme
and
others
Pharmacology and Toxicology
Zr-labeled N4MU01 radioimmunoconjugates as theranostics against nectin-4 positive triple negative breast cancer
20 February 2025 by
H. Babeker
and
others
Pharmacology and Toxicology
A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis
19 February 2025 by
S. Teworte
and
others
at
University of Bern
Pharmacology and Toxicology
Mycotoxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model
14 February 2025 by
Mariangela Morelli
and
K. Queiroz
Pharmacology and Toxicology
Transcutaneous delivery of disease specific PI3K/Akt/mTOR inhibitor based hybrid nanoparticles in hydrogel system for the management of psoriasis: Insights from in vivo studies
13 February 2025 by
Rohit Keshari
and
others
Pharmacology and Toxicology
A fluorescent probe enables the discovery of improved antagonists targeting the intracellular allosteric site of the chemokine receptor CCR7
12 February 2025 by
S. Wurnig
and
others
at
University of Bonn
Pharmacology and Toxicology
Free acid β-hydroxybutyrate supplementation does not ameliorate dextran sodium sulfate-induced colitis similar to ketogenic diet in male mice
12 February 2025 by
L. Toivio
and
others
Pharmacology and Toxicology
In Vitro Evaluation of Anti-Inflammatory, Anti-Plaque Efficacy, and Biocompatibility of Norway Spruce (Picea abies) Resin Extract for Oral Care Applications
7 February 2025 by
K. Yamileva
and
others
Pharmacology and Toxicology
Machine learning enables high-throughput, low-replicate screening for novel anti-seizure targets and compounds using combined movement and calcium fluorescence in larval zebrafish
4 February 2025 by
C. Mcgraw
and
A. Poduri
at
Massachusetts General Hospital
Pharmacology and Toxicology
Adjusted vascular contractility relies on integrity of progranulin pathway: Insights into mitochondrial function
3 February 2025 by
Shubham Singh
and
others
Pharmacology and Toxicology
Caution when using network partners for target identification in drug discovery
24 January 2025 by
Donghui Tan
and
others
at
McGill University
Pharmacology and Toxicology
The protective roles of Eugenol on type 1 diabetes mellitus through NRF2 mediated oxidative stress pathway
10 January 2025 by
Yuyang Jiang
and
others
Pharmacology and Toxicology
DigiLoCS: A Leap Forward in Predictive Organ-on-Chip Simulations
9 January 2025 by
M. Aravindakshan
and
others
Pharmacology and Toxicology
stormTB: A web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments.
8 January 2025 by
Roberto Visintainer
and
others
Pharmacology and Toxicology
Differential biotransformation ability may alter fish biodiversity in polluted waters
5 January 2025 by
M. Franco
and
others
Pharmacology and Toxicology
PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression
30 December 2024 by
M. Antwi
and
others
Pharmacology and Toxicology
Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
27 December 2024 by
Yu Sun
and
others
Pharmacology and Toxicology
A Mechanistic Approach to Optimize Combination Antibiotic Therapy
24 December 2024 by
Fabrizio Clarelli
and
others
Pharmacology and Toxicology
Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
9 December 2024 by
J. Paris
and
others
Pharmacology and Toxicology
Riluzole reverses blood-testis barrier loss to rescue chemotherapy induced male infertility by binding to TRPC
6 December 2024 by
Ruizheng Huang
and
others
at
Jinan University
Pharmacology and Toxicology
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