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Chemical Biology
Visualizing biomolecules within living microglia in complex environments using a clickable small fluorogenic compound
2 days ago by
Wonju Kim
and
others
Biological and Medicinal Chemistry
,
Biochemistry
Activity-Based Chemoproteomic Profiling Reveals the Active Kinome of Leishmania
3 days ago by
Exequiel O. J. Porta
and
others
Biological and Medicinal Chemistry
,
Chemical Biology
Chemistry of Scorpion Venom and its Medicinal Potential
4 days ago by
Shreerang Joshi
and
others
Biological and Medicinal Chemistry
,
Biochemistry
Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives
7 days ago by
Markus Haener
and
others
at
University of Freiburg
Biological and Medicinal Chemistry
,
Organic Chemistry
Programmable Site-Selectivity: pH-Modulated Triazine-Thiol Exchange for Site- and Chemoselective Cysteine Labelling
17 April 2025 by
Katerina Gavriel
and
others
at
Radboud University
Biological and Medicinal Chemistry
,
Organic Chemistry
Indirect Ubiquitination: Noncovalent Ubiquitin Tethering Independent of Endogenous Ubiquitination Machinery for Targeted Protein Degradation
17 April 2025 by
Takafumi Furuhata
and
others
Biological and Medicinal Chemistry
,
Chemical Biology
Fluorescence Quenching Properties and Bioimaging Applications of Readily Accessible Blue to Far-Red Fluorogenic Triazinium Salts
10 April 2025 by
Veronika Šlachtová
and
others
Biological and Medicinal Chemistry
,
Chemical Biology
Mitochondria-targeting abasic site-reactive probe (mTAP) enables the manipulation of mitochondrial DNA repair and turnover
9 April 2025 by
Anal Jana
and
others
at
UC Riverside
Biological and Medicinal Chemistry
,
Organic Chemistry
Reaction-based Ratiometric Sensors for Imaging Bio-Analytes in Living Cells Using Spontaneous Raman Scattering
9 April 2025 by
Sujit Kumar Das
and
others
at
Tata Institute of Fundamental Research
Biological and Medicinal Chemistry
,
Chemical Biology
Regio- and Stereoselective Synthesis of Nitro-fatty Acids as NRF2 Pathway Activators Working under Ambient or Hypoxic Conditions
8 April 2025 by
Daniel Chrenko
and
others
at
Palacký University Olomouc
Biological and Medicinal Chemistry
,
Organic Chemistry
Fluorescence Quenching Properties and Bioimaging Applications of Readily Accessible Blue to Far-Red Fluorogenic Triazinium Salts
8 April 2025 by
Veronika Šlachtová
and
others
Biological and Medicinal Chemistry
,
Chemical Biology
Discovery of Novel EGFR Kinase Inhibitors Using a Wild-Type EGFR: A Computational Approach
7 April 2025 by
Dhrubajyoti Maji
Biological and Medicinal Chemistry
,
Bioinformatics and Computational Biology
A general and accessible approach to enrichment and characterisation of natural anti-Neu5Gc antibodies from human samples
7 April 2025 by
Esme Hutton
and
others
at
University of York
Biological and Medicinal Chemistry
,
Biochemistry
bis(trifluoromethyl)-carborhodamines: highly fluorogenic, far-red to near infrared dyes for live cell fluorescence microscopy, activity-based sensing, and single-molecule microscopy
3 April 2025 by
Nels Gerstner
and
others
at
UC Berkeley
Biological and Medicinal Chemistry
,
Organic Chemistry
Accessing Ultralarge Chemical Spaces via a Sociable Fragment Library: Design and Crystallographic Screening
2 April 2025 by
Philipp Janssen
and
others
at
University of Münster
Theoretical and Computational Chemistry
,
Biological and Medicinal Chemistry
µMap-FFPE: A High-Resolution Protein Proximity Labeling Platform for Formalin-Fixed Paraffin-Embedded Tissue Samples
1 April 2025 by
Noah Bissonnette
and
others
at
Princeton University
Biological and Medicinal Chemistry
,
Organic Chemistry
Molecularly defined glycocalyx models reveal AB5 toxins recognize their target glycans superselectively
19 March 2025 by
Laia Saltor Núñez
and
others
at
University of Leeds
Biological and Medicinal Chemistry
,
Polymer Science
Dynamics and Interplay of the Binding Pockets in the Glycine Receptor
19 March 2025 by
Guangpeng Xue
and
others
at
King's College London
Theoretical and Computational Chemistry
,
Physical Chemistry
Amino Acid Profile of Selected Arthropod Hemolymph in Zaria, Kaduna State, Nigeria
18 March 2025 by
Jocelyn Agbanu
and
others
at
Nigerian Defence Academy
Biological and Medicinal Chemistry
,
Cell and Molecular Biology
Ascorbate Peroxidase (APEX2) Activates Dihydrotetrazine Oxidation for Rapid Bioorthogonal Chemistry in Living Cells
18 March 2025 by
Sophia Neglia
and
others
at
University of Delaware
Biological and Medicinal Chemistry
,
Organic Chemistry
A mild protecting-group free strategy for neoglycoconjugate synthesis
18 March 2025 by
Princey Raju
and
others
at
University of Alberta
Biological and Medicinal Chemistry
,
Chemical Biology
A novel photoaffinity probe for analysing the phosphatdylinositol 5-phosphate interactome
14 March 2025 by
Glen Brodie
and
others
at
UC Los Angeles
Biological and Medicinal Chemistry
,
Chemical Biology
Abiotic Transcription Factors by Strategic Insertion of Non-Proteinogenic Amino Acids
13 March 2025 by
Omer Harel
and
others
at
Tel Aviv University
Biological and Medicinal Chemistry
,
Biochemistry
Organocatalytic switches of OGG1 control ultrafast abasic site incision through compound pKa
13 March 2025 by
Mario Kehler
and
others
at
Karolinska Institutet
Biological and Medicinal Chemistry
,
Biochemistry
Intrinsic Visible Emission of Amyloid-β Oligomers: A Potential Tool for Early Alzheimer’s Diagnosis
13 March 2025 by
Mercedes Novo
and
others
Biological and Medicinal Chemistry
,
Chemical Biology
Next-Level Bioorthogonal Bond-Cleavage Through Intramolecular Control of Click-To-Release Chemistry
13 March 2025 by
Walter Kuba
and
others
at
Tu Wien
Biological and Medicinal Chemistry
,
Organic Chemistry
Reactive Quantum-Mechanical Molecular Dynamics Simulations to Reveal Mechanisms of Enzyme Catalysis
12 March 2025 by
Rae Ann Corrigan Grove
and
others
Theoretical and Computational Chemistry
,
Biological and Medicinal Chemistry
DNA-programmable Protein Degradation: Dynamic Control of PROTAC Activity via DNA Hybridization and Strand Displacement
11 March 2025 by
Disha Kashyap
and
others
at
University of Oxford
Biological and Medicinal Chemistry
,
Organic Chemistry
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening
10 March 2025 by
Andreas Holmqvist
and
others
Biological and Medicinal Chemistry
,
Cell and Molecular Biology
Solvent Reorganization in Stabilized Protein-Polymer Conjugates Visualized by 2D IR and NMR Spectroscopy
7 March 2025 by
Raiza Maia
and
others
at
University of Texas at Austin
Physical Chemistry
,
Biological and Medicinal Chemistry
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