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12
Ribosomal Frameshifting Selectively Modulates the Biosynthesis, Assembly, and Function of a Misfolded CFTR Variant
10 October 2024 by
P. Carmody
and
others
Biochemistry
Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants
25 January 2024 by
E. Mcdonald
and
others
at
Vanderbilt University
Bioinformatics
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer`s disease by improving synaptic function and proteostasis
4 April 2023 by
C. Duran Aniotz
and
others
at
Universidad de Chile
Animal Behavior and Cognition
Identification of replication fork-associated proteins in Drosophila embryos and cultured cells using iPOND coupled to quantitative mass spectrometry
28 April 2022 by
A. Munden
and
others
at
Vanderbilt University
Biochemistry
Distinct proteostasis states drive pharmacologic chaperone susceptibility for Cystic Fibrosis Transmembrane Conductance Regulator misfolding mutants
7 April 2022 by
E. Mcdonald
and
others
at
Vanderbilt University
Cell Biology
A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
2 December 2021 by
B. Reisman
and
others
at
Vanderbilt University
Biochemistry
Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs
27 June 2021 by
K. Almasy
and
others
at
Vanderbilt University
Biochemistry
Glycosylation Limits Forward Trafficking of the Tetraspan Membrane Protein PMP22
30 April 2021 by
J. Marinko
and
others
at
Vanderbilt University
Cell Biology
Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration
5 February 2021 by
R. Vidal
and
others
Neuroscience
Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies
2 December 2020 by
J. Davies
and
others
at
Vanderbilt University
Biochemistry
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates
8 July 2020 by
P. Garcia-Huerta
and
others
Neuroscience
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein
16 May 2019 by
L. Plate
and
others
at
The Scripps Research Institute
Cell Biology
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation using Targeted RNA-sequencing
10 March 2019 by
J. M. D. Grandjean
and
others
at
The Scripps Research Institute
Cell Biology
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Biochemistry
Cell Biology
Neuroscience
Bioinformatics
Animal Behavior and Cognition