Articles by R. L. Kember

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R. L. Kember

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Divergent gene expression in alcohol and opioid usedisorders results in consistent alterations in functional networks in the Dorsolateral Prefrontal Cortex

14 October 2024 by Mitchell Macdonald and others

Neuroscience

Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits

23 July 2024 by E. Hartwell and others

Genetic and Genomic Medicine

The Relationship between Alcohol- and Sleep-related Traits: Results from Polygenic Risk Score Analyses and Mendelian Randomization Studies

28 July 2023 by Sounak Chakravorty and others

Addiction Medicine

Genetic underpinnings of the transition from alcohol consumption to alcohol use disorder: shared and unique genetic architectures in a cross-ancestry sample

7 June 2023 by R. Kember and others

Genetic and Genomic Medicine

Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program

5 May 2023 by Yulan Cheng and others at

Yale University

Genetics

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population

7 March 2023 by E. Humphries and others at

University of Maryland School of Medicine

Psychiatry and Clinical Psychology

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain

28 September 2022 by R. Kember and others at

University of Pennsylvania

Genetic and Genomic Medicine

Phenome-wide association analysis of substance use disorders in a deeply phenotyped sample

18 August 2022 by R. Kember and others at

University of Pennsylvania

Genetic and Genomic Medicine

Integrating Human Brain Proteomic Data with Genome-Wide Association Study Findings Identifies Novel Brain Proteins in Substance Use Traits

8 August 2022 by S. Toikumo and others at

University of Pennsylvania

Genetic and Genomic Medicine

Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry.

25 July 2022 by J. Deak and others

Addiction Medicine

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.

2 June 2022 by M. Vujkovic and others

Genetic and Genomic Medicine

Identifying high-risk comorbidities of short and long-term opioid prescription use

2 June 2022 by M. Jennings and others

Addiction Medicine

History of suicide attempts and COVID-19 infection in Veterans with schizophrenia or schizoaffective disorder: effect modification by age and obesity

1 December 2021 by O. Okusaga and others

Psychiatry and Clinical Psychology

Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank

30 November 2021 by L. Wang and others

Genetic and Genomic Medicine

Evidence of shared genetic influences underlying schizophrenia and alcohol use disorder, but not alcohol consumption

7 July 2021 by E. Johnson and others

Genetic and Genomic Medicine

Ancestral Haplotype Reconstruction in Endogamous Populations using Identity-By-Descent

26 February 2021 by K. Finke and others at

Haverford College

Bioinformatics

Exome-by-phenome-wide rare variant gene burden association with electronic health record phenotypes

11 January 2021 by Jeongju Park and others

Genomics

GWAS including 82,707 subjects identifies functional coding variant in OPRM1 gene associated with opioid use disorder

3 June 2020 by Huaikang Zhou and others

Genetic and Genomic Medicine

Meta-analysis of problematic alcohol use in 435,563 individuals identifies 29 risk variants and yields insights into biology, pleiotropy and causality

25 May 2020 by Huaikang Zhou and others at

Yale School of Medicine

Genetics

Genetic pleiotropy between mood disorders, metabolic, and endocrine traits in a multigenerational pedigree

12 October 2018 by R. Kember and others at

University of Pennsylvania

Genetics

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Genetic and Genomic Medicine Addiction Medicine Genetics Psychiatry and Clinical Psychology Bioinformatics Genomics