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Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers

By E. Nakagaki-Silva and others at
LogoUniversity of Cambridge
Alternative splicing (AS) programs are primarily controlled by regulatory RNA binding proteins (RBPs). It has been proposed that a small number of master splicing regulators might control cell-specific splicing networks and that these RBPs could be identified by proximity of their genes to transcriptional super-enhancers. Using this approach we identified... Show more
July 8, 2019
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Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers
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