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BMP signaling is necessary and sufficient for osteoarthritis and a target for disease modifying therapy

By A. Jaswal and others at
LogoUniversity of Aberdeen
and
LogoBanaras Hindu University
ObjectiveTo investigate the role of BMP signaling in osteoarthritis' pathogenesis and propose a disease-modifying therapy for OA. MethodsC57BL6/J mouse line was used to perform ACLT surgery at P120 to study the expression pattern of the BMP signaling readout pSMAD1/5/9. To investigate whether activation of BMP signaling is sufficient and necessary to... Show more
June 30, 2023
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