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Computational identification of antibody-binding epitopes from mimotope datasets

By Ronghan Li and others at
LogoBoston University
A fundamental challenge in computational vaccinology is that most B-cell epitopes are conformational and therefore hard to predict from sequence alone. Another significant challenge is that a great deal of the amino acid sequence of a viral surface protein might not in fact be antigenic. Thus, identifying the regions of... Show more
February 23, 2024
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