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Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale

By G. Voth and others at
LogoUniversity of Chicago
The sarcoplasmic reticulum Ca2+-ATPase (SERCA) transports two Ca2+ ions from the cytoplasm to the reticulum lumen at the expense of ATP hydrolysis. In addition to transporting Ca2+, SERCA facilitates bidirectional proton transport across the sarcoplasmic reticulum to maintain the charge balance of the transport sites and to balance the charge... Show more
August 6, 2020
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Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale
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