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CFTR-mediated monocyte-macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons

By Xīlíng Zhāng and others
Cystic fibrosis (CF) is an inherited disorder caused by biallelic mutations of the cystic fibrosis transmembrane conductance regulator gene (CFTR). Converging lines of evidence suggest that CF carriers with only one defective CFTR copy are at increased risk for CF-related conditions and pulmonary infections, but the molecular mechanisms underpinning this... Show more
March 21, 2022
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CFTR-mediated monocyte-macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons
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