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Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator

By N. Claassens and others
Formate can be directly produced from CO2 and renewable electricity, making it a promising microbial feedstock for sustainable bioproduction. Cupriavidus necator is one of the few biotechnologically-relevant hosts that can grow on formate, but it uses the inefficient Calvin cycle. Here, we redesign C. necator metabolism for formate assimilation via... Show more
August 15, 2020
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Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator
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