Structure of the γ-tubulin ring complex-capped microtubule

Microtubules are composed of /{beta}-tubulin dimers positioned head-to-tail to form protofilaments that associate laterally in varying numbers. It is not known how cellular microtubules assemble with the canonical 13-protofilament architecture, resulting in micrometer-scale /{beta}-tubulin tracks for intracellular transport that align with, rather than spiral along, the filaments long-axis. We report... Show more