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Spatially resolved profiling of protein conformation and interactions by biocompatible chemical cross-linking in living cells

By Linzhen Zhao and others
The protein structures and interactions that maintain and regulate cellular processes in different subcellular organelles are heterogeneous and dynamic. However, it remains challenging to characterize the subcellular specificity and translocation of protein complexes in terms of conformation and interactions. Herein, we developed a spatially resolved protein complex profiling approach by... Show more
September 27, 2024
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Spatially resolved profiling of protein conformation and interactions by biocompatible chemical cross-linking in living cells
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