Sign in

RosettaGPCR: Multiple Template Homology Modeling of GPCRs with Rosetta

By Brendan Bender and others at
LogoUC San Francisco
G-protein coupled receptors (GPCRs) represent a significant target class for pharmaceutical therapies. However, to date, only about 10% of druggable GPCRs have had their structures characterized at atomic resolution. Further, because of the flexibility of GPCRs, alternative conformations remain to be modeled, even after an experimental structure is available. Thus,... Show more
October 28, 2020
=
0
Loading PDF…
Loading full text...
Similar articles
Loading recommendations...
=
0
x1
RosettaGPCR: Multiple Template Homology Modeling of GPCRs with Rosetta
Click on play to start listening