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Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes

By Nandan Malhotra and Aswin Sai Narain Seshasayee at
LogoTata Institute of Fundamental Research
Bacterial genome organisation is primarily driven by chromosome replication from a single origin of replication. However chromosomal rearrangements, which can disrupt such organisation, are inevitable in nature. Long DNA repeats are major players mediating rearrangements, large and small, via homologous recombination. Since changes to genome organisation affect bacterial fitness -... Show more
July 1, 2022
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Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes
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