Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD+, Causes Reductive Stress, and Suppresses Glycolysis and Cell Growth

In the present study, we developed a chemical method to produce dihydro nicotinamide mononucleotide (NMNH), which is the reduced-form of nicotinamide mononucleotide (NMN). We demonstrated that NMNH was a better NAD+ enhancer compared to NMN both in vitro and in vivo mediated by NMNAT. Additionally, NMNH increased the reduced NAD... Show more