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Structure Prediction and Synthesis of a New Class of Macrocyclic Peptide Natural Products

By Graham Hudson and others
<p>Owing to advances in genomic sequencing and bioinformatics, the breadth of natural product biosynthetic gene clusters (BGCs) has meteorically risen. This remains true for ribosomally synthesized and post-translationally modified peptides (RiPPs), where the rate of bioinformatically identifying clusters vastly outpaces characterization efforts. Uniting bioinformatics and enzymological knowledge to predict the... Show more
March 12, 2020
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Structure Prediction and Synthesis of a New Class of Macrocyclic Peptide Natural Products
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