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PBAF’s genomic binding dynamics are regulated via bromodomain-acetyl-lysine interactions and select chromatin states

By C. Kenworthy and others at
LogoAlbert Einstein College of Medicine
Transcriptional bursting involves genes rapidly switching between active and inactive states. Chromatin remodelers actively target arrays of acetylated nucleosomes at select enhancers and promoters to facilitate or shut down the repeated recruitment of RNA Pol II during transcriptional bursting. It is unknown how acetylated chromatin is dynamically targeted and regulated... Show more
March 30, 2022
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PBAF’s genomic binding dynamics are regulated via bromodomain-acetyl-lysine interactions and select chromatin states
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