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Miltefosine Impacts Small Molecule Transport in Gram-Positive Bacteria

By Marea Blake and others
Miltefosine (MLT) is an alkylphosphocholine with clinical success as an anticancer and antiparasitic drug. Although the mechanism of action of MLT is highly debated, the interaction of MLT with the membrane, specifically lipid rafts of eukaryotes, is well-documented. Recent reports suggest MLT impacts the functional membrane microdomains in bacteria -... Show more
May 8, 2024
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Miltefosine Impacts Small Molecule Transport in Gram-Positive Bacteria
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