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Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

By Joachim Hamm and others
Hexokinases (HK) catalyze the first step of glycolysis and thereby limit its pace. HK2 is highly expressed in the gut epithelium, plays a role in immune responses and is upregulated in inflammation and ulcerative colitis 1-3. Here, we examined the microbial regulation of HK2 and its impact on intestinal inflammation... Show more
November 29, 2021
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Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
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