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Human Genes Escaping X-inactivation Revealed by Single Cell Expression Data

By K. Wainer Katsir and Michal Linial at
LogoHebrew University of Jerusalem
BackgroundIn mammals, sex chromosomes pose an inherent imbalance of gene expression between sexes. In each female somatic cell, random inactivation of one of the X-chromosomes restores this balance. While most genes from the inactivated X-chromosome are silenced, 15-25% are known to escape X-inactivation (termed escapees). The expression levels of these... Show more
March 14, 2019
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Human Genes Escaping X-inactivation Revealed by Single Cell Expression Data
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