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Mechanical and kinetic factors drive sorting of F-actin crosslinkers on bundles

By S. Freedman and others at
LogoNew York University
In cells, actin binding proteins (ABPs) sort to different regions in order to establish F-actin networks with diverse functions, including filopodia used for cell migration, or contractile rings required for cell division. Recent experimental work uncovered a passive mechanism that may facilitate spatial localization of ABPs: binding of a short... Show more
July 25, 2019
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Mechanical and kinetic factors drive sorting of F-actin crosslinkers on bundles
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