Sign in

Location bias contributes to functionally selective responses of biased CXCR3 agonists

By D. Eiger and others
Some G protein-coupled receptor (GPCR) ligands act as "biased agonists" which preferentially activate specific signaling transducers over others. Although GPCRs are primarily found at the plasma membrane, GPCRs can traffic to and signal from many subcellular compartments. Here, we determine that differential subcellular signaling contributes to the biased signaling generated... Show more
October 4, 2022
=
0
Loading PDF…
Loading full text...
Similar articles
Loading recommendations...
=
0
x1
Location bias contributes to functionally selective responses of biased CXCR3 agonists
Click on play to start listening