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Limitations in next-generation sequencing-based genotyping of breast cancer polygenic risk score loci

By Anton Baumann and others
Considering polygenic risk scores (PRSs) in individual risk prediction is increasingly becoming the standard in genetic testing for hereditary breast cancer (BC). To calculate individual BC risks, the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) with inclusion of the BCAC 313 or the BRIDGES 306... Show more
June 21, 2024
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Limitations in next-generation sequencing-based genotyping of breast cancer polygenic risk score loci
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