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The transcription factor E2A drives neural differentiation in pluripotent cells

By Christopher Rao and others at
LogoUniversity of Edinburgh
The intrinsic mechanisms that link extracellular signalling to the onset of neural differentiation are not well understood. In pluripotent mouse cells, BMP blocks entry into the neural lineage via transcriptional upregulation of Inhibitor of Differentiation (Id) factors. We have previously identified that the major binding partner of Id proteins in... Show more
June 2, 2020
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The transcription factor E2A drives neural differentiation in pluripotent cells
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