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Heterologous Biosynthesis of Cotylenol and Concise Synthesis of Fusicoccane Diterpenoids

By Zhenhua Guan and others
Fusicoccane diterpenoids have attracted intensive attention due to their complex structures as well as diverse biological activities. Here we report a novel strategy for the synthesis of cotylenol and other fusicoccane diterpenoids. By harnessing the biosynthetic pathways of brassicicenes and fusicoccins, cotylenol was produced in an engineered Aspergillus oryzae strain.... Show more
June 11, 2024
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Heterologous Biosynthesis of Cotylenol and Concise Synthesis of Fusicoccane Diterpenoids
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