Exploring the Structural Diversity of Novel 3-Substituted Coumarins as Potent Inhibitors of Tumor-Associated Carbonic Anhydrases: Expanding the Pharmacological Space for Anticancer Drug Discovery

Innovations in cancer chemotherapy continue to occupy the priority list of demands to ensure our health security. The vast chemical space provides a plethora of anticancer discovery opportunities, however, limited by the boundaries of synthetic feasibility. This study aims at expanding the established pharmacological space of tumor-associated carbonic anhydrases by... Show more