Dynamic combinatorial chemistry for the multiplexed identification of glyco-dyn[n]arenes in an anti-adhesive strategy against Pseudomonas aeruginosa

Carbohydrate-protein interactions are of prime importance in cell-cell communication, signal transduction, cancer, bacterial or viral infection. Chemists have designed multivalent systems to mimick these recognition phenomena and provide potent ligands of these proteins with foreseen therapeutic applications. Dynamic combinatorial chemistry provides access to a library of chemical species in equilibrium... Show more