Sign in

DYNA: Disease-Specific Language Model for Variant Pathogenicity

By Huixin Zhan and Zijun Zhang at
LogoCedars-Sinai Medical Center
Clinical variant classification of pathogenic versus benign genetic variants remains a challenge in clinical genetics. Recently, the proposition of genomic foundation models has improved the generic variant effect prediction (VEP) accuracy via weakly-supervised or unsupervised training. However, these VEPs are not disease-specific, limiting their adaptation at the point of care.... Show more
May 31, 2024
=
0
Loading PDF…
Loading full text...
Similar articles
Loading recommendations...
=
0
x1
DYNA: Disease-Specific Language Model for Variant Pathogenicity
Click on play to start listening