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Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates

By Jae Hoon Sul and others at
LogoUC Los Angeles
Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP) in numerous multigenerational pedigrees suggests that, in such families, large-effect inherited variants might play a greater role.... Show more
February 24, 2020
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Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates
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