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Comparative untargeted metabolomic profiling of induced mitochondrial fusion in pancreatic cancer

By Nhat Duy Nguyen and others
Mitochondria are dynamic organelles that constantly alter their shape through the recruitment of specialized proteins, like mitofusin-2 (Mfn2) and dynamin-related protein 1 (Drp1). Mfn2 induces the fusion of nearby mitochondria, while Drp1 mediates mitochondrial fission. We previously found that the genetic or pharmacological activation of mitochondrial fusion was tumor suppressive... Show more
September 15, 2021
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Comparative untargeted metabolomic profiling of induced mitochondrial fusion in pancreatic cancer
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