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Anticancer activity of 4-aryl-1,4-dihydropyridines

By Tatalina Oliveira and others at
LogoUniversidade de São Paulo
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cy-totoxicity to three human cancer cell lines viz. U-251MG (human glioblastoma), HeLa 229 (human cervical adenocarcinoma), and MCF-7 (human breast carcinoma). None of the 1,4-DHPs were cytotoxic to U-251MG cells.... Show more
July 10, 2024
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Anticancer activity of 4-aryl-1,4-dihydropyridines
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