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Affinity-Based Covalent Sialyltransferase Probes Enabled by Ligand-Directed Chemistry

By Jun Yang Ong and others at
LogoUtrecht University
Sialyltransferases (ST) are enzymes found in among others mammals and bacteria that are responsible for producing sialylated glycans, which are known to play important roles in human health and disease. An example of the latter being the opportunistic molecular mimicry by pathogenic bacteria. However, chemical tools to study sialyltransferases have... Show more
July 10, 2024
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Affinity-Based Covalent Sialyltransferase Probes Enabled by Ligand-Directed Chemistry
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