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A domino reaction strategy for facile and modular construction of synthetically challenging functionalized ortho-fluoroanilines

By Benedikt Grau and others at
LogoFriedrich-Alexander Universität Erlangen-Nürnberg
and
LogoGeorg-August-Universität Göttingen
The selective formation of ortho-fluoroanilines, representing versatile intermediates for the pharmaceutical and fine chemical industries, relies to date on, e.g., transition-metal-catalyzed fluorination of azobenzenes, which must be pre-formed from aniline derivatives. While few efficient methods for aniline synthesis were reported, sustainable, straightforward, and selective synthesis of fluoroanilines, and in particular... Show more
July 9, 2024
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A domino reaction strategy for facile and modular construction of synthetically challenging functionalized ortho-fluoroanilines
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