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RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair

By T. Yasuhara and others at
LogoGunma University
R-loops, consisting of ssDNA and DNA-RNA hybrids, are potentially vulnerable unless they are appropriately processed. Recent evidence suggests that R-loops can form in the proximity of DNA double-strand breaks (DSBs) within transcriptionally active regions. Yet, how the vulnerability of R-loops is overcome during DSB repair remains unclear. Here, we identify... Show more
February 1, 2022
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RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair
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