Sign in

Microglia Clear Neuron-released α-Synuclein via Selective Autophagy and Prevent Neurodegeneration

By Inho Choi and others at
LogoIcahn School of Medicine at Mount Sinai
Microglia maintain brain homeostasis by removing neuron-derived components such as myelin and cell debris. The evidence linking microglia to neurodegenerative diseases is growing, however, the precise mechanisms remain poorly understood. Herein we report a neuroprotective role for microglia in the clearance of neuron-released -synuclein. Neuronal -synuclein activates microglia, which in... Show more
March 13, 2020
=
0
Loading PDF…
Loading full text...
Similar articles
Loading recommendations...
=
0
x1
Microglia Clear Neuron-released α-Synuclein via Selective Autophagy and Prevent Neurodegeneration
Click on play to start listening