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A circadian clock in the blood-brain barrier regulates xenobiotic efflux from the brain

By S. Zhang and others
HighlightsO_LIThe Drosophila BBB displays a circadian rhythm of permeability\nC_LIO_LICyclic efflux driven by a clock in the BBB underlies the permeability rhythm\nC_LIO_LICircadian control is non-cell-autonomous via gap junction regulation of [Mg2+]i\nC_LIO_LIAn anti-seizure drug is more effective when administered at night\nC_LI\n\nSummaryEndogenous circadian rhythms are thought to modulate responses to external factors, but... Show more
February 27, 2018
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A circadian clock in the blood-brain barrier regulates xenobiotic efflux from the brain
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