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Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus.

By K. Rienecker and others at
LogoUC Merced
The transcriptional profile of immediate early genes (IEGs) is indicative of the duration of neuronal activity, but it is unknown whether it affected by the strength of depolarization. Also unknown is whether an activity history of graded potential changes influences further neuronal activity. In this work with dissociated rat cortical... Show more
July 19, 2022
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Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus.
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