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A conserved requirement for Fbxo7 during male germ cell cytoplasmic remodelling

By C. Rathje and others at
LogoUniversity of Cambridge
Summary statementFbxo7 is the substrate-recognition subunit of an SCF-type ubiquitin E3 ligase complex. It has physiologically important functions in regulating mitophagy, proteasome activity and the cell cycle in multiple cell types, like neurons, lymphocytes and erythrocytes. Here we show that in addition to the previously-known Parkinsonian and haematopoietic phenotypes, Fbxo7-deficient... Show more
October 10, 2019
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A conserved requirement for Fbxo7 during male germ cell cytoplasmic remodelling
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