Sign in

Proton Coupling and the Multiscale Kinetic Mechanism of a Peptide Transporter

By C. Li and others at
LogoUniversity of Chicago
Proton coupled peptide transporters (POTs) are crucial for the uptake of di- and tri-peptides as well as drug and pro-drug molecules in prokaryotes and eukaryotic cells. We illustrate from multiscale modeling how transmembrane proton flux couples within a POT protein to drive essential steps of the full functional cycle: 1)... Show more
May 25, 2022
=
0
Loading PDF…
Loading full text...
Similar articles
Loading recommendations...
=
0
x1
Proton Coupling and the Multiscale Kinetic Mechanism of a Peptide Transporter
Click on play to start listening