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CellPhoneDB v5: inferring cell-cell communication from single-cell multiomics data
13 November 2023 by
Kevin Troulé
and
others
at
Wellcome Sanger Institute
Cell Behavior
,
Quantitative Methods
MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio High Fidelity reads
18 July 2023 by
M. Uliano-Silva
and
others
at
Wellcome Sanger Institute
Bioinformatics
SUNi mutagenesis: scalable and uniform nicking for efficient generation of variant libraries
7 July 2023 by
T. Mighell
and
others
at
Wellcome Sanger Institute
Genomics
An endosymbiont harvest: Phylogenomic analysis of Wolbachia genomes from the Darwin Tree of Life biodiversity genomics project
23 January 2023 by
E. Vancaester
and
Mark Blaxter
at
Wellcome Sanger Institute
Genomics
Efficient generation of mNeonGreen Plasmodium falciparum reporter lines enables quantitative fitness analysis
16 September 2022 by
J. Hoshizaki
and
others
at
Wellcome Sanger Institute
Genetics
A manually curated annotation characterises genomic features of P. falciparum lncRNAs
30 November 2022 by
J. Hoshizaki
and
others
at
Wellcome Sanger Institute
Genomics
High-throughput deep learning variant effect prediction with Sequence UNET
10 May 2023 by
A. Dunham
and
others
at
Wellcome Sanger Institute
Bioinformatics
Barcoding genetically distinct Plasmodium falciparum strains for comparative assessment of fitness and antimalarial drug resistance
16 August 2022 by
Maria Carrasquilla
and
others
at
Wellcome Sanger Institute
Microbiology
CRISPRcleanR WebApp: an interactive web application for processing genome-wide pooled CRISPR-Cas9 viability screen
3 January 2023 by
A. Vinceti
and
others
at
Wellcome Sanger Institute
Bioinformatics
Screening for functional regulatory variants in open chromatin using GenIE-ATAC
1 May 2023 by
S. Cooper
and
others
at
Wellcome Sanger Institute
Genetics
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
20 October 2022 by
Kazuya Murai
and
others
at
Wellcome Sanger Institute
Cancer Biology
Clonal diversification and histogenesis of malignant germ cell tumours
11 August 2022 by
T. R. W. Oliver
and
others
at
Wellcome Sanger Institute
Cancer Biology
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
26 May 2022 by
B. Soskic
and
others
at
Wellcome Sanger Institute
Genomics
Robust temporal map of human in vitro myelopoiesis using single-cell genomics
24 May 2022 by
C. Alsinet
and
others
at
Wellcome Sanger Institute
Developmental Biology
A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens
2 April 2022 by
Samuel Price
and
others
at
Wellcome Sanger Institute
Cancer Biology
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
8 July 2022 by
P. Robinson
and
others
at
Wellcome Sanger Institute
Genomics
Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon
10 November 2021 by
Tyler Sanderson
and
J. Barrett
at
Wellcome Sanger Institute
Epidemiology
Predicting base editing outcomes using position-specific sequence determinants
1 March 2022 by
A. Pallaseni
and
others
at
Wellcome Sanger Institute
Genetics
The longitudinal dynamics and natural history of clonal haematopoiesis
1 June 2022 by
M. Fabre
and
others
at
Wellcome Sanger Institute
Cancer Biology
Precancer: Mutant clones in normal epithelium outcompete and eliminate esophageal micro-tumors
13 October 2021 by
B. Colom
and
others
at
Wellcome Sanger Institute
Cancer Biology
CoRe: A robustly benchmarked R package for the identification of core fitness genes in genome-wide pooled CRISPR knock-out screens
17 November 2021 by
A. Vinceti
and
others
at
Wellcome Sanger Institute
Bioinformatics
The transcriptome of Schistosoma mansoni developing eggs reveals key mediators in pathogenesis and life cycle propagation.
18 August 2021 by
Zongfei Lü
and
others
at
Wellcome Sanger Institute
Developmental Biology
Panakeia - A universal tool for bacterial pangenome analysis
5 April 2022 by
Sofie Beier
and
N. Thomson
at
Wellcome Sanger Institute
Bioinformatics
Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for Saturation Genome Editing and other Deep Mutational Scanning experiments
11 November 2021 by
L. Barbon
and
others
at
Wellcome Sanger Institute
Genomics
The mutational landscape of human somatic and germline cells
16 September 2022 by
Lesa Moore
and
others
at
Wellcome Sanger Institute
Genomics
InDelible: Detection and Evaluation of Clinically-relevant Structural Variation from Exome Sequencing
8 October 2021 by
E. Gardner
and
others
at
Wellcome Sanger Institute
Genetic and Genomic Medicine
Defining the early stages of intestinal colonisation by whipworms
1 April 2022 by
M. A. Duque Correa
and
others
at
Wellcome Sanger Institute
Immunology
Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases
30 September 2021 by
P. Robinson
and
others
at
Wellcome Sanger Institute
Genomics
Sex-biased reduction in reproductive success drives selective constraint on human genes
23 March 2022 by
E. Gardner
and
others
at
Wellcome Sanger Institute
Genetics
Alternative splicing modulation by G-quadruplexes
3 May 2022 by
I. Georgakopoulos Soares
and
others
at
Wellcome Sanger Institute
Genomics
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Topics
Genomics
Bioinformatics
Cancer Biology
Genetics
Microbiology
Developmental Biology
Immunology
Epidemiology
Genetic and Genomic Medicine
Cell Biology
Cell Behavior
Quantitative Methods
Infectious Diseases
Evolutionary Biology
Molecular Biology
