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Children's Hospital of Philadelphia
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The Children's Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science
3 November 2022 by
J. Lilly
and
others
at
Children's Hospital of Philadelphia
Cancer Biology
Remarkable Sex-Specific Differences at Single-Cell Resolution in Neonatal Hyperoxic Lung Injury
26 October 2022 by
M. E. Cantu Gutierrez
and
others
at
Children's Hospital of Philadelphia
Developmental Biology
Enriching Representation Learning Using 53 Million Patient Notes through Human Phenotype Ontology Embedding
28 February 2023 by
M. Daniali
and
others
at
Children's Hospital of Philadelphia
Bioinformatics
Surface anchoring of the Kingella kingae galactan is dependent on the lipopolysaccharide O-antigen
7 September 2022 by
N. Montoya
and
others
at
Children's Hospital of Philadelphia
Microbiology
A recurrent de novo splice site variant involving DNM1 alternative exon 10a causes developmental and epileptic encephalopathy through a dominant-negative mechanism
21 November 2022 by
Shreyas Parthasarathy
and
others
at
Children's Hospital of Philadelphia
Genetics
Nicotinamide Riboside alleviates exercise intolerance in ANT1-deficient mice.
6 August 2022 by
P. Schaefer
and
others
at
Children's Hospital of Philadelphia
Physiology
Two type II phosphatidylinositol 4-kinases function sequentially in tubule-mediated cargo delivery from early endosomes to melanosomes
5 May 2022 by
Yapeng Zhu
and
others
at
Children's Hospital of Philadelphia
Cell Biology
Transient late gestation prenatal hypoxic insult results in functional deficits but not gross neuroanatomic deficits in mice
11 March 2022 by
A. Cristancho
and
others
at
Children's Hospital of Philadelphia
Animal Behavior and Cognition
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
27 September 2022 by
J. Foster
and
others
at
Children's Hospital of Philadelphia
Cancer Biology
Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria parasites
29 December 2021 by
P. Frasse
and
others
at
Children's Hospital of Philadelphia
Microbiology
Stability of Polygenic Scores Across Discovery Genome-Wide Association Studies
21 January 2022 by
L. Schultz
and
others
at
Children's Hospital of Philadelphia
Genetics
FTY720 (Fingolimod), a modulator of sphingosine-1-phosphate receptors, increases baseline hypothalamic-pituitary adrenal axis activity and alters behaviors relevant to affect and anxiety
12 August 2021 by
B. Corbett
and
others
at
Children's Hospital of Philadelphia
Neuroscience
Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 isolates from Pennsylvania
4 June 2021 by
A. Moustafa
and
others
at
Children's Hospital of Philadelphia
Genomics
Restriction enzyme selection dictates detection range sensitivity in chromatin conformation capture-based variant-to-gene mapping approaches
18 August 2021 by
Crystal Su
and
others
at
Children's Hospital of Philadelphia
Genomics
Structure-guided microbial targeting of antistaphylococcal prodrugs
19 July 2021 by
Jim Miller
and
others
at
Children's Hospital of Philadelphia
Biochemistry
LIQA: Long-read Isoform Quantification and Analysis
17 June 2021 by
Y. Hu
and
others
at
Children's Hospital of Philadelphia
Bioinformatics
ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression
4 November 2020 by
Xiukai Lan
and
others
at
Children's Hospital of Philadelphia
Molecular Biology
The malaria metabolite HMBPP does not trigger erythrocyte terpene production
23 September 2020 by
Jim Miller
and
A. R. Odom John
at
Children's Hospital of Philadelphia
Biochemistry
Neuroanatomical underpinning of diffusion kurtosis measurements in the cerebral cortex of healthy macaque brains
15 October 2020 by
Tiffany Zhu
and
others
at
Children's Hospital of Philadelphia
Neuroscience
Antimicrobial prodrug activation by the staphylococcal glyoxalase GloB
29 October 2020 by
M. Mikati
and
others
at
Children's Hospital of Philadelphia
Microbiology
A computational tool for direct inference of cell-specific expression profiles and cellular composition from bulk-tissue RNA-seq in brain disorders
22 June 2021 by
A. Doostparast Torshizi
and
others
at
Children's Hospital of Philadelphia
Systems Biology
Cell type-specific proteogenomic signal diffusion for integrating multi-omics data predicts novel schizophrenia risk genes
2 September 2020 by
A. Doostparast Torshizi
and
others
at
Children's Hospital of Philadelphia
Systems Biology
Novel BRAF gene fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers
11 February 2021 by
Pavitra Jain
and
others
at
Children's Hospital of Philadelphia
Cancer Biology
Implications of error-prone long-read whole-genome shotgun sequencing on characterizing reference microbiomes
2 June 2020 by
Y. Hu
and
others
at
Children's Hospital of Philadelphia
Genomics
SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation
23 September 2020 by
M. Marks
and
others
at
Children's Hospital of Philadelphia
Cell Biology
Phosphatidylinositol-4-kinase IIα licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells
27 October 2020 by
C. Lopez-Haber
and
others
at
Children's Hospital of Philadelphia
Cell Biology
Protein prenylation and Hsp40 in thermotolerance of Plasmodium falciparum malaria parasites
29 June 2021 by
E. Mathews
and
others
at
Children's Hospital of Philadelphia
Microbiology
annoFuse: an R Package to annotate and prioritize putative oncogenic RNA fusions
14 December 2020 by
K. Gaonkar
and
others
at
Children's Hospital of Philadelphia
Bioinformatics
Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex
27 July 2020 by
Daniel Blumenthal
and
others
at
Children's Hospital of Philadelphia
Immunology
Structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma
14 August 2020 by
Gilberto López
and
others
at
Children's Hospital of Philadelphia
Cancer Biology
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Bioinformatics
Cancer Biology
Microbiology
Genomics
Genetics
Cell Biology
Neuroscience
Biochemistry
Systems Biology
Developmental Biology
Physiology
Animal Behavior and Cognition
Molecular Biology
Immunology
Evolutionary Biology