Articles by Leiden University Medical Center

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Leiden University Medical Center

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When accurate prediction models yield harmful self-fulfilling prophecies

26 August 2024 by Wouter A. C. Van Amsterdam and others at

Leiden University Medical Center

Methodology, Machine Learning

Single-cell reference mapping to construct and extend cell type hierarchies

26 July 2023 by L. Michielsen and others at

Leiden University Medical Center

Bioinformatics

The inactive X chromosome accumulates widespread epigenetic variability with age

25 August 2023 by Yuanliu liu and others at

Leiden University Medical Center

Genetics

Prehospital triage of intracranial hemorrhage and anterior large vessel occlusion ischemic stroke

9 August 2023 by Lex Dekker and others at

Leiden University Medical Center

Neurology

Cell type matching across species using protein embeddings and transfer learning

25 May 2023 by K. Biharie and others at

Leiden University Medical Center

Bioinformatics

Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development

23 December 2022 by M. SchöNke and others at

Leiden University Medical Center

Physiology

ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation

12 December 2022 by Xuemeng Cao and others at

Leiden University Medical Center

Developmental Biology

Natural Language Processing Methods to Identify Oncology Patients at High Risk for Acute Care with Clinical Notes

16 March 2023 by Claudio Fanconi and others at

Leiden University Medical Center

Computation and Language, Machine Learning

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

17 January 2023 by C. Liu and others at

Leiden University Medical Center

Pathology

Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry

23 January 2023 by L. Vermij and others at

Leiden University Medical Center

Oncology

A four-point molecular handover during Okazaki maturation

24 August 2023 by M. Botto and others at

Leiden University Medical Center

Biochemistry

SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells

21 November 2022 by C. Pothast and others at

Leiden University Medical Center

Immunology

Pressure-driven fluidic system to control, multiplex and recirculate cell culture medium for Organs-on-Chips

22 August 2022 by M. N. S. De Graaf and others at

Leiden University Medical Center

Bioengineering

Comparison of Very Short Answer Questions and Multiple Choice Questions in Medical Students: Reliability, Discrimination, Acceptability and Effect on Knowledge Retention

14 July 2023 by R. Janse and others at

Leiden University Medical Center

Medical Education

Carriage of three plasmids in a single human clinical isolate of Clostridioides difficile

23 December 2022 by A. Roseboom and others at

Leiden University Medical Center

Microbiology

Spectral flow cytometry reveals metabolic heterogeneity in tissue macrophages

12 September 2023 by G. Heieis and others at

Leiden University Medical Center

Immunology

TopoGAN: Unsupervised manifold alignment of single-cell data

25 November 2023 by Abhijay Singh and others at

Leiden University Medical Center

Bioinformatics

SIQ: easy quantitative measurement of mutation profiles in sequencing data

5 September 2022 by R. Van Schendel and others at

Leiden University Medical Center

Bioinformatics

Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice

3 June 2022 by A. Zawistowska-Deniziak and others at

Leiden University Medical Center

Immunology

A Systematic Review of Human Challenge Trials, Designs, and Safety

11 October 2022 by J. Adams-Phipps and others at

Leiden University Medical Center

Infectious Diseases

Single-cell immune profiling reveals novel thymus-seeding populations, T cell commitment, and multi-lineage development in the human thymus

18 November 2022 by Moritz Cordes and others at

Leiden University Medical Center

Immunology

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment

15 July 2022 by C. L. R. Van Doorn and others at

Leiden University Medical Center

Infectious Diseases

Performance of five metagenomic classifiers for virus pathogen detection using respiratory samples from a clinical cohort

14 March 2022 by E. Carbo and others at

Leiden University Medical Center

Infectious Diseases

STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells

22 September 2022 by C. Grandela and others at

Leiden University Medical Center

Cell Biology

Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals

29 March 2022 by W. Huisman and others at

Leiden University Medical Center

Immunology

The relationship between human thymus-derived regulatory T cells, TGF-β-induced regulatory T cells and conventional CD4+ T cells as revealed by proteomics

25 November 2022 by M. Mensink and others at

Leiden University Medical Center

Immunology

The association between lymphocyte mitochondrial DNA abundance and Stroke: a combination of multivariable-adjusted survival and mendelian randomization analyses

19 June 2022 by L. Martens and others at

Leiden University Medical Center

Cardiovascular Medicine

Longitudinal monitoring of DNA viral loads in transplant patients using quantitative metagenomic next-generation sequencing

14 February 2022 by E. Carbo and others at

Leiden University Medical Center

Infectious Diseases

MRI-based classification of neuropsychiatric systemic lupus erythematosus patients with self-supervised contrastive learning

16 February 2022 by F. Inglese and others at

Leiden University Medical Center

Radiology and Imaging

pmTR database: population matched (PM) germline allelic variants of T-cell receptor (TR) loci

18 April 2022 by Joey Dekker and others at

Leiden University Medical Center

Immunology

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Microbiology Bioinformatics Immunology Infectious Diseases Genetics Biochemistry Machine Learning Oncology Physiology Cell Biology Epidemiology Molecular Biology Genomics Neurology Cardiovascular Medicine