Articles by St. Jude Children's Research Hospital

Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia

8 June 2023 by B. Bergeron and others at

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

24 November 2022 by R. K. S. Malireddi and others at

Quantifying coexistence concentrations in multi-component phase-separating systems using analytical HPLC

17 October 2022 by Anne Bremer and others at

A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

Biophysics

12 September 2022 by L. Wang and others at

A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset

Neuroscience

19 September 2022 by Qiaobo Li and others at

A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis

Bioinformatics

18 February 2022 by Linfeng Fan and others at

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

13 December 2021 by J. Rybak and others at

The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma

Microbiology

27 April 2022 by A. Patel and others at

YAP/TAZ Maintain the Proliferative Capacity and Structural Organization of Radial Glial Cells During Brain Development

19 August 2021 by A. Lavado and others at

A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

Developmental Biology

10 September 2021 by Akito Inoue and others at

Ubiquitination is essential for recovery of cellular activities followingheat shock

25 June 2021 by B. Maxwell and others at

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.

9 November 2021 by Minjie Pan and others at

Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains

20 December 2021 by Anne Bremer and others at

DNA demethylation switches the drivers of Foxp3 expression to maintain regulatory T cell identity

Biophysics

14 December 2022 by J. Li and others at

Surprising Phenotypic Diversity of Cancer-associated mutations of Gly 34 in the Histone H3 tail

1 February 2021 by B. Lowe and others at

COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death

Molecular Biology

19 November 2020 by Ramesh Karki and others at

Zika virus alters centrosome organization to suppress the innate immune response

6 July 2022 by A. Kodani and others at

High fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

27 January 2021 by B. Freibaum and others at

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation

12 February 2021 by N. Milkovic and others at

MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation

Biophysics

20 October 2020 by J. Craig and others at

Broadly reactive influenza antibodies are not limited by germinal center competition with high affinity antibodies

3 November 2020 by Ryan Keating and others at

Functional Interrogation of HOXA9 Regulome in MLLr Leukemia via Reporter-based CRISPR/Cas9 screen

1 October 2020 by H. Zhang and others at

Heme-Sensing Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

7 December 2020 by Kelly Helm Smith and others at

The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program

16 April 2020 by Binita Mondal and others at

Za2 domain of ZBP1 is a molecular switch regulating Influenza-induced PANoptosis and perinatal lethality during development

Molecular Biology

30 April 2020 by S. Kesavardhana and others at

Experimental Evolution in vivo to Identify Selective Pressures During Pneumococcal Colonization

12 May 2020 by V. Cooper and others at

Astrovirus Replication Is Inhibited by Nitazoxanide In Vitro and In Vivo

Microbiology

28 November 2019 by V. Hargest and others at

Siah2 integrates mitogenic and extracellular matrix signalslinking neuronal progenitor ciliogenesis with germinal zoneoccupancy.

Microbiology

20 October 2020 by Theresa Ong and others at

MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma

Neuroscience

14 February 2020 by M. Zeineldin and others at